The lungs work together with the respiratory system by working together to help the body to breath, the lungs also pump air into the blood.The lungs are where the body is able to engage in gas exchange between the blood and the air. The circulatory system sends deoxygenated blood to the lungs, where it is again oxygenated and returned to the heart, so it can be pumped to tissues and organs throughout body.Various sensors and receptors in the lungs are sensitive to inflation, deflation, and chemical stimulation, and can activate the nervous system. Afferent signals sent from the respiratory system can initiate neurally-controlled responses such as a coughreflex or changes in the breathing pattern.